COE | Non-COE | ||||
---|---|---|---|---|---|
N | % | N | % | p-value | |
Demographicsa | |||||
Age | |||||
< 65 | 533 | 46.2% | 23,390 | 55.0% | |
65–74 | 324 | 28.1% | 10,369 | 24.4% | < 0.0001 |
75–80 | 86 | 7.5% | 2679 | 6.3% | |
80–85 | 94 | 8.1% | 2842 | 6.7% | |
85+ | 117 | 10.1% | 3244 | 7.6% | |
Male | 1087 | 94.2% | 38,823 | 91.3% | 0.001 |
White | 1053 | 91.2% | 34,752 | 81.7% | < 0.0001 |
Medication use | |||||
Estrogen | 2 | 0.2% | 38 | 0.1% | 0.285 |
Hormone deprivation meds | 7 | 0.6% | 93 | 0.2% | 0.017 |
Seizure meds | 1 | 0.1% | 45 | 0.1% | 0.656 |
Steroid | 141 | 12.2% | 1244 | 2.9% | < 0.0001 |
Testosterone | 42 | 3.6% | 718 | 1.7% | < 0.0001 |
Comorbidities | |||||
Alcohol | 7 | 0.6% | 113 | 0.3% | 0.040 |
Diabetes | 47 | 4.1% | 513 | 1.2% | < 0.0001 |
Fall | 34 | 2.9% | 370 | 0.9% | < 0.0001 |
Hyperparathyroidism | 8 | 0.7% | 83 | 0.2% | 0.003 |
Malnutrition | 56 | 4.9% | 598 | 1.4% | < 0.0001 |
Prior fracture | 6 | 0.5% | 161 | 0.4% | 0.460 |
Renal disease | 108 | 9.4% | 1027 | 2.4% | < 0.0001 |
Rheumatoid arthritis | 16 | 1.4% | 203 | 0.5% | < 0.0001 |
Smoking | 207 | 17.9% | 4196 | 9.9% | < 0.0001 |
Stroke | 30 | 2.6% | 462 | 1.1% | < 0.0001 |
Vitamin D deficiency | 23 | 2.0% | 505 | 1.2% | 0.019 |